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Speech-Stimulating Substances in Autism Spectrum Disorders

Autism spectrum disorder (ASD) is characterized by the core domains of persistent deficits in social communication and restricted-repetitive patterns of behaviors, interests, or activities. A heterogeneous and complex set of neurodevelopmental conditions are grouped in the spectrum. Pro-inflammatory...

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Autores principales: Castillo, María Andrea, Urdaneta, Kendy Eduardo, Semprún-Hernández, Neomar, Brigida, Anna Lisa, Antonucci, Nicola, Schultz, Stephen, Siniscalco, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616660/
https://www.ncbi.nlm.nih.gov/pubmed/31212856
http://dx.doi.org/10.3390/bs9060060
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author Castillo, María Andrea
Urdaneta, Kendy Eduardo
Semprún-Hernández, Neomar
Brigida, Anna Lisa
Antonucci, Nicola
Schultz, Stephen
Siniscalco, Dario
author_facet Castillo, María Andrea
Urdaneta, Kendy Eduardo
Semprún-Hernández, Neomar
Brigida, Anna Lisa
Antonucci, Nicola
Schultz, Stephen
Siniscalco, Dario
author_sort Castillo, María Andrea
collection PubMed
description Autism spectrum disorder (ASD) is characterized by the core domains of persistent deficits in social communication and restricted-repetitive patterns of behaviors, interests, or activities. A heterogeneous and complex set of neurodevelopmental conditions are grouped in the spectrum. Pro-inflammatory events and immune system dysfunctions are cellular and molecular events associated with ASD. Several conditions co-occur with ASD: seizures, gastro-intestinal problems, attention deficit, anxiety and depression, and sleep problems. However, language and speech issues are key components of ASD symptoms current therapies find difficult to face. Several speech-stimulating substances have been shown to be effective in increasing speech ability in ASD subjects. The need for large clinical trials to determine safety and efficacy is recommended.
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spelling pubmed-66166602019-07-18 Speech-Stimulating Substances in Autism Spectrum Disorders Castillo, María Andrea Urdaneta, Kendy Eduardo Semprún-Hernández, Neomar Brigida, Anna Lisa Antonucci, Nicola Schultz, Stephen Siniscalco, Dario Behav Sci (Basel) Review Autism spectrum disorder (ASD) is characterized by the core domains of persistent deficits in social communication and restricted-repetitive patterns of behaviors, interests, or activities. A heterogeneous and complex set of neurodevelopmental conditions are grouped in the spectrum. Pro-inflammatory events and immune system dysfunctions are cellular and molecular events associated with ASD. Several conditions co-occur with ASD: seizures, gastro-intestinal problems, attention deficit, anxiety and depression, and sleep problems. However, language and speech issues are key components of ASD symptoms current therapies find difficult to face. Several speech-stimulating substances have been shown to be effective in increasing speech ability in ASD subjects. The need for large clinical trials to determine safety and efficacy is recommended. MDPI 2019-06-12 /pmc/articles/PMC6616660/ /pubmed/31212856 http://dx.doi.org/10.3390/bs9060060 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Castillo, María Andrea
Urdaneta, Kendy Eduardo
Semprún-Hernández, Neomar
Brigida, Anna Lisa
Antonucci, Nicola
Schultz, Stephen
Siniscalco, Dario
Speech-Stimulating Substances in Autism Spectrum Disorders
title Speech-Stimulating Substances in Autism Spectrum Disorders
title_full Speech-Stimulating Substances in Autism Spectrum Disorders
title_fullStr Speech-Stimulating Substances in Autism Spectrum Disorders
title_full_unstemmed Speech-Stimulating Substances in Autism Spectrum Disorders
title_short Speech-Stimulating Substances in Autism Spectrum Disorders
title_sort speech-stimulating substances in autism spectrum disorders
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616660/
https://www.ncbi.nlm.nih.gov/pubmed/31212856
http://dx.doi.org/10.3390/bs9060060
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