Animal Models to Study Mucormycosis

Mucormycosis is a rare but often fatal or debilitating infection caused by a diverse group of fungi. Animal models have been crucial in advancing our knowledge of mechanisms influencing the pathogenesis of mucormycoses, and to evaluate therapeutic strategies. This review describes the animal models...

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Detalles Bibliográficos
Autor principal: Jacobsen, Ilse D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617025/
https://www.ncbi.nlm.nih.gov/pubmed/30934788
http://dx.doi.org/10.3390/jof5020027
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author Jacobsen, Ilse D.
author_facet Jacobsen, Ilse D.
author_sort Jacobsen, Ilse D.
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description Mucormycosis is a rare but often fatal or debilitating infection caused by a diverse group of fungi. Animal models have been crucial in advancing our knowledge of mechanisms influencing the pathogenesis of mucormycoses, and to evaluate therapeutic strategies. This review describes the animal models established for mucormycosis, summarizes how they have been applied to study mucormycoses, and discusses the advantages and limitations of the different model systems.
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spelling pubmed-66170252019-07-18 Animal Models to Study Mucormycosis Jacobsen, Ilse D. J Fungi (Basel) Review Mucormycosis is a rare but often fatal or debilitating infection caused by a diverse group of fungi. Animal models have been crucial in advancing our knowledge of mechanisms influencing the pathogenesis of mucormycoses, and to evaluate therapeutic strategies. This review describes the animal models established for mucormycosis, summarizes how they have been applied to study mucormycoses, and discusses the advantages and limitations of the different model systems. MDPI 2019-03-27 /pmc/articles/PMC6617025/ /pubmed/30934788 http://dx.doi.org/10.3390/jof5020027 Text en © 2019 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Jacobsen, Ilse D.
Animal Models to Study Mucormycosis
title Animal Models to Study Mucormycosis
title_full Animal Models to Study Mucormycosis
title_fullStr Animal Models to Study Mucormycosis
title_full_unstemmed Animal Models to Study Mucormycosis
title_short Animal Models to Study Mucormycosis
title_sort animal models to study mucormycosis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617025/
https://www.ncbi.nlm.nih.gov/pubmed/30934788
http://dx.doi.org/10.3390/jof5020027
work_keys_str_mv AT jacobsenilsed animalmodelstostudymucormycosis

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