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Methodologies for Analyzing Soluble Organic Compounds in Extraterrestrial Samples: Amino Acids, Amines, Monocarboxylic Acids, Aldehydes, and Ketones

Soluble organic compositions of extraterrestrial samples offer valuable insights into the prebiotic organic chemistry of the solar system. This review provides a summary of the techniques commonly used for analyzing amino acids, amines, monocarboxylic acids, aldehydes, and ketones in extraterrestria...

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Autores principales: Simkus, Danielle N., Aponte, José C., Elsila, Jamie E., Parker, Eric T., Glavin, Daniel P., Dworkin, Jason P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617175/
https://www.ncbi.nlm.nih.gov/pubmed/31174308
http://dx.doi.org/10.3390/life9020047
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author Simkus, Danielle N.
Aponte, José C.
Elsila, Jamie E.
Parker, Eric T.
Glavin, Daniel P.
Dworkin, Jason P.
author_facet Simkus, Danielle N.
Aponte, José C.
Elsila, Jamie E.
Parker, Eric T.
Glavin, Daniel P.
Dworkin, Jason P.
author_sort Simkus, Danielle N.
collection PubMed
description Soluble organic compositions of extraterrestrial samples offer valuable insights into the prebiotic organic chemistry of the solar system. This review provides a summary of the techniques commonly used for analyzing amino acids, amines, monocarboxylic acids, aldehydes, and ketones in extraterrestrial samples. Here, we discuss possible effects of various experimental factors (e.g., extraction protocols, derivatization methods, and chromatographic techniques) in order to highlight potential influences on the results obtained from different methodologies. This detailed summary and assessment of current techniques is intended to serve as a basic guide for selecting methodologies for soluble organic analyses and to emphasize some key considerations for future method development.
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spelling pubmed-66171752019-07-18 Methodologies for Analyzing Soluble Organic Compounds in Extraterrestrial Samples: Amino Acids, Amines, Monocarboxylic Acids, Aldehydes, and Ketones Simkus, Danielle N. Aponte, José C. Elsila, Jamie E. Parker, Eric T. Glavin, Daniel P. Dworkin, Jason P. Life (Basel) Review Soluble organic compositions of extraterrestrial samples offer valuable insights into the prebiotic organic chemistry of the solar system. This review provides a summary of the techniques commonly used for analyzing amino acids, amines, monocarboxylic acids, aldehydes, and ketones in extraterrestrial samples. Here, we discuss possible effects of various experimental factors (e.g., extraction protocols, derivatization methods, and chromatographic techniques) in order to highlight potential influences on the results obtained from different methodologies. This detailed summary and assessment of current techniques is intended to serve as a basic guide for selecting methodologies for soluble organic analyses and to emphasize some key considerations for future method development. MDPI 2019-06-06 /pmc/articles/PMC6617175/ /pubmed/31174308 http://dx.doi.org/10.3390/life9020047 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Simkus, Danielle N.
Aponte, José C.
Elsila, Jamie E.
Parker, Eric T.
Glavin, Daniel P.
Dworkin, Jason P.
Methodologies for Analyzing Soluble Organic Compounds in Extraterrestrial Samples: Amino Acids, Amines, Monocarboxylic Acids, Aldehydes, and Ketones
title Methodologies for Analyzing Soluble Organic Compounds in Extraterrestrial Samples: Amino Acids, Amines, Monocarboxylic Acids, Aldehydes, and Ketones
title_full Methodologies for Analyzing Soluble Organic Compounds in Extraterrestrial Samples: Amino Acids, Amines, Monocarboxylic Acids, Aldehydes, and Ketones
title_fullStr Methodologies for Analyzing Soluble Organic Compounds in Extraterrestrial Samples: Amino Acids, Amines, Monocarboxylic Acids, Aldehydes, and Ketones
title_full_unstemmed Methodologies for Analyzing Soluble Organic Compounds in Extraterrestrial Samples: Amino Acids, Amines, Monocarboxylic Acids, Aldehydes, and Ketones
title_short Methodologies for Analyzing Soluble Organic Compounds in Extraterrestrial Samples: Amino Acids, Amines, Monocarboxylic Acids, Aldehydes, and Ketones
title_sort methodologies for analyzing soluble organic compounds in extraterrestrial samples: amino acids, amines, monocarboxylic acids, aldehydes, and ketones
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617175/
https://www.ncbi.nlm.nih.gov/pubmed/31174308
http://dx.doi.org/10.3390/life9020047
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