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Indoleamine-2,3-Dioxygenase in Thyroid Cancer Cells Suppresses Natural Killer Cell Function by Inhibiting NKG2D and NKp46 Expression via STAT Signaling Pathways

Natural killer (NK) cells are key players in the immune system. They use receptors on their cell surface to identify target cells. However, to escape being killed by the immune system, cancer cells such as thyroid cancer cells, use various methods to suppress the function of NK cells. Thus, this stu...

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Detalles Bibliográficos
Autores principales: Park, Arum, Yang, Yunjeong, Lee, Yunhee, Kim, Mi Sun, Park, Young-Jun, Jung, Haiyoung, Kim, Tae-Don, Lee, Hee Gu, Choi, Inpyo, Yoon, Suk Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617210/
https://www.ncbi.nlm.nih.gov/pubmed/31212870
http://dx.doi.org/10.3390/jcm8060842