Cargando…

Utility of CT and MRI in assessment of mandibular involvement in oral cavity cancer()

OBJECTIVE: Oral cavity squamous cell carcinoma (SCC) may present with early invasion of mandibular bone. Preoperative planning of surgery is essential considering patient's postoperative quality of life. Our purpose was to evaluate the efficacy of computer tomography scan (CT) and magnetic reso...

Descripción completa

Detalles Bibliográficos
Autores principales: Nae, Andreea, O'Leary, Gerard, Feeley, Linda, Fives, Cassie, Fitzgerald, Brendan, Chiriac, Elena, Sheahan, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617213/
https://www.ncbi.nlm.nih.gov/pubmed/31334484
http://dx.doi.org/10.1016/j.wjorl.2019.02.001
_version_ 1783433640342978560
author Nae, Andreea
O'Leary, Gerard
Feeley, Linda
Fives, Cassie
Fitzgerald, Brendan
Chiriac, Elena
Sheahan, Patrick
author_facet Nae, Andreea
O'Leary, Gerard
Feeley, Linda
Fives, Cassie
Fitzgerald, Brendan
Chiriac, Elena
Sheahan, Patrick
author_sort Nae, Andreea
collection PubMed
description OBJECTIVE: Oral cavity squamous cell carcinoma (SCC) may present with early invasion of mandibular bone. Preoperative planning of surgery is essential considering patient's postoperative quality of life. Our purpose was to evaluate the efficacy of computer tomography scan (CT) and magnetic resonance imaging (MRI) in detecting mandibular bone involvement in oral SCC. METHODS: A retrospective study was conducted on 98 patients with SCC of floor of mouth, lower alveolus and retromolar trigone operated on with curative intent. Preoperative CT and MRI scans were re-reviewed by a consultant radiologist and original histology slides were re-reviewed by 3 pathologists. RESULTS: Forty-five patients were included in the final study. Combined CT and MRI had a sensitivity of 100% and a specificity of 72%. CONCLUSION: The results suggest that combined CT and MRI have diagnostic utility in detecting mandibular invasion by oral cancer, but with a significant false positive rate.
format Online
Article
Text
id pubmed-6617213
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher KeAi Publishing
record_format MEDLINE/PubMed
spelling pubmed-66172132019-07-22 Utility of CT and MRI in assessment of mandibular involvement in oral cavity cancer() Nae, Andreea O'Leary, Gerard Feeley, Linda Fives, Cassie Fitzgerald, Brendan Chiriac, Elena Sheahan, Patrick World J Otorhinolaryngol Head Neck Surg Research Paper OBJECTIVE: Oral cavity squamous cell carcinoma (SCC) may present with early invasion of mandibular bone. Preoperative planning of surgery is essential considering patient's postoperative quality of life. Our purpose was to evaluate the efficacy of computer tomography scan (CT) and magnetic resonance imaging (MRI) in detecting mandibular bone involvement in oral SCC. METHODS: A retrospective study was conducted on 98 patients with SCC of floor of mouth, lower alveolus and retromolar trigone operated on with curative intent. Preoperative CT and MRI scans were re-reviewed by a consultant radiologist and original histology slides were re-reviewed by 3 pathologists. RESULTS: Forty-five patients were included in the final study. Combined CT and MRI had a sensitivity of 100% and a specificity of 72%. CONCLUSION: The results suggest that combined CT and MRI have diagnostic utility in detecting mandibular invasion by oral cancer, but with a significant false positive rate. KeAi Publishing 2019-03-22 /pmc/articles/PMC6617213/ /pubmed/31334484 http://dx.doi.org/10.1016/j.wjorl.2019.02.001 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Paper
Nae, Andreea
O'Leary, Gerard
Feeley, Linda
Fives, Cassie
Fitzgerald, Brendan
Chiriac, Elena
Sheahan, Patrick
Utility of CT and MRI in assessment of mandibular involvement in oral cavity cancer()
title Utility of CT and MRI in assessment of mandibular involvement in oral cavity cancer()
title_full Utility of CT and MRI in assessment of mandibular involvement in oral cavity cancer()
title_fullStr Utility of CT and MRI in assessment of mandibular involvement in oral cavity cancer()
title_full_unstemmed Utility of CT and MRI in assessment of mandibular involvement in oral cavity cancer()
title_short Utility of CT and MRI in assessment of mandibular involvement in oral cavity cancer()
title_sort utility of ct and mri in assessment of mandibular involvement in oral cavity cancer()
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617213/
https://www.ncbi.nlm.nih.gov/pubmed/31334484
http://dx.doi.org/10.1016/j.wjorl.2019.02.001
work_keys_str_mv AT naeandreea utilityofctandmriinassessmentofmandibularinvolvementinoralcavitycancer
AT olearygerard utilityofctandmriinassessmentofmandibularinvolvementinoralcavitycancer
AT feeleylinda utilityofctandmriinassessmentofmandibularinvolvementinoralcavitycancer
AT fivescassie utilityofctandmriinassessmentofmandibularinvolvementinoralcavitycancer
AT fitzgeraldbrendan utilityofctandmriinassessmentofmandibularinvolvementinoralcavitycancer
AT chiriacelena utilityofctandmriinassessmentofmandibularinvolvementinoralcavitycancer
AT sheahanpatrick utilityofctandmriinassessmentofmandibularinvolvementinoralcavitycancer