Timing of Treatment with the Flavonoid 7,8-DHF Critically Impacts on Its Effects on Learning and Memory in the Ts65Dn Mouse

No therapies currently exist for intellectual disability in Down syndrome (DS). In view of its similarities with DS, including learning and memory (L&M) defects, the Ts65Dn mouse model of DS is widely used for the design of therapy. 7,8-dihydroxyflavone (7,8-DHF), a flavonoid that targets the tr...

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Detalles Bibliográficos
Autores principales: Giacomini, Andrea, Stagni, Fiorenza, Emili, Marco, Uguagliati, Beatrice, Rimondini, Roberto, Bartesaghi, Renata, Guidi, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617346/
https://www.ncbi.nlm.nih.gov/pubmed/31174258
http://dx.doi.org/10.3390/antiox8060163

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