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Depression and incident hip fracture: A longitudinal follow-up study using a national sample cohort
The aim of the present study was to evaluate the risk of hip fracture in depression patients using a nationwide cohort population. Data from the Korean National Health Insurance Service-National Sample Cohort for a population ≥50 years of age from 2002 to 2013 were collected. The 25,197 individuals...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617478/ https://www.ncbi.nlm.nih.gov/pubmed/31261597 http://dx.doi.org/10.1097/MD.0000000000016268 |
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author | Kim, So Young Lee, Joon Kyu Oh, Dong Jun Kong, Il Gyu Choi, Hyo Geun |
author_facet | Kim, So Young Lee, Joon Kyu Oh, Dong Jun Kong, Il Gyu Choi, Hyo Geun |
author_sort | Kim, So Young |
collection | PubMed |
description | The aim of the present study was to evaluate the risk of hip fracture in depression patients using a nationwide cohort population. Data from the Korean National Health Insurance Service-National Sample Cohort for a population ≥50 years of age from 2002 to 2013 were collected. The 25,197 individuals with depression were matched for age, sex, income, region of residence, hypertension, diabetes, and dyslipidemia, with 100,788 individuals comprising the control group. In both the depression and control groups, history of hip fracture was evaluated. Using the International Classification of Disease-10 (ICD-10) codes, depression (F31–F39), and hip fracture (S720, S721, and S722) were investigated. The crude and adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) of hip fracture in depression patients were analyzed using a Cox proportional hazard model. Subgroup analyses were conducted according to age and sex. In the depression group, 1.1% (277/25,197) of the subjects had hip fracture, and 0.7% (693/100,095) in the control group had hip fracture (P <.001). The depression group demonstrated a higher adjusted HR for hip fracture than the control group (adjusted HR = 1.46, 95% CI = 1.27–1.68, P <.001). This result was consistent in the ≥65 years old subgroups. The risk of hip fracture was elevated in depression patients. |
format | Online Article Text |
id | pubmed-6617478 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-66174782019-07-22 Depression and incident hip fracture: A longitudinal follow-up study using a national sample cohort Kim, So Young Lee, Joon Kyu Oh, Dong Jun Kong, Il Gyu Choi, Hyo Geun Medicine (Baltimore) Research Article The aim of the present study was to evaluate the risk of hip fracture in depression patients using a nationwide cohort population. Data from the Korean National Health Insurance Service-National Sample Cohort for a population ≥50 years of age from 2002 to 2013 were collected. The 25,197 individuals with depression were matched for age, sex, income, region of residence, hypertension, diabetes, and dyslipidemia, with 100,788 individuals comprising the control group. In both the depression and control groups, history of hip fracture was evaluated. Using the International Classification of Disease-10 (ICD-10) codes, depression (F31–F39), and hip fracture (S720, S721, and S722) were investigated. The crude and adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) of hip fracture in depression patients were analyzed using a Cox proportional hazard model. Subgroup analyses were conducted according to age and sex. In the depression group, 1.1% (277/25,197) of the subjects had hip fracture, and 0.7% (693/100,095) in the control group had hip fracture (P <.001). The depression group demonstrated a higher adjusted HR for hip fracture than the control group (adjusted HR = 1.46, 95% CI = 1.27–1.68, P <.001). This result was consistent in the ≥65 years old subgroups. The risk of hip fracture was elevated in depression patients. Wolters Kluwer Health 2019-06-28 /pmc/articles/PMC6617478/ /pubmed/31261597 http://dx.doi.org/10.1097/MD.0000000000016268 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 |
spellingShingle | Research Article Kim, So Young Lee, Joon Kyu Oh, Dong Jun Kong, Il Gyu Choi, Hyo Geun Depression and incident hip fracture: A longitudinal follow-up study using a national sample cohort |
title | Depression and incident hip fracture: A longitudinal follow-up study using a national sample cohort |
title_full | Depression and incident hip fracture: A longitudinal follow-up study using a national sample cohort |
title_fullStr | Depression and incident hip fracture: A longitudinal follow-up study using a national sample cohort |
title_full_unstemmed | Depression and incident hip fracture: A longitudinal follow-up study using a national sample cohort |
title_short | Depression and incident hip fracture: A longitudinal follow-up study using a national sample cohort |
title_sort | depression and incident hip fracture: a longitudinal follow-up study using a national sample cohort |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617478/ https://www.ncbi.nlm.nih.gov/pubmed/31261597 http://dx.doi.org/10.1097/MD.0000000000016268 |
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