Very Low-Density Lipoproteins of Metabolic Syndrome Modulates STIM1, Suppresses Store-Operated Calcium Entry, and Deranges Myofilament Proteins in Atrial Myocytes

Individuals with metabolic syndrome (MetS) are at high risk for atrial myopathy and atrial fibrillation. Very low-density lipoproteins (VLDLs) of MetS (MetS-VLDLs) are cytotoxic to atrial myocytes in vivo and in vitro. The calcineurin–nuclear factor of activated T-cells (NFAT) pathway, which is regu...

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Detalles Bibliográficos
Autores principales: Shiou, Yi-Lin, Lin, Hsin-Ting, Ke, Liang-Yin, Wu, Bin-Nan, Shin, Shyi-Jang, Chen, Chu-Huang, Tsai, Wei-Chung, Chu, Chih-Sheng, Lee, Hsiang-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617489/
https://www.ncbi.nlm.nih.gov/pubmed/31226824
http://dx.doi.org/10.3390/jcm8060881

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