Retroposed copies of RET gene: a somatically acquired event in medullary thyroid carcinoma

BACKGROUND: Different pathogenic germline mutations in the RET oncogene are identified in MEN 2, a hereditary syndrome characterized by medullary thyroid carcinoma (MTC) and other endocrine tumors. Although genetic predisposition is recognized, not all RET mutation carriers will develop the disease...

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Detalles Bibliográficos
Autores principales: Bim, Larissa V., Navarro, Fábio C. P., Valente, Flávia O. F., Lima-Junior, José V., Delcelo, Rosana, Dias-da-Silva, Magnus R., Maciel, Rui M. B., Galante, Pedro A. F., Cerutti, Janete M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617568/
https://www.ncbi.nlm.nih.gov/pubmed/31288802
http://dx.doi.org/10.1186/s12920-019-0552-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617568/
https://www.ncbi.nlm.nih.gov/pubmed/31288802
http://dx.doi.org/10.1186/s12920-019-0552-1

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