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Retroposed copies of RET gene: a somatically acquired event in medullary thyroid carcinoma
BACKGROUND: Different pathogenic germline mutations in the RET oncogene are identified in MEN 2, a hereditary syndrome characterized by medullary thyroid carcinoma (MTC) and other endocrine tumors. Although genetic predisposition is recognized, not all RET mutation carriers will develop the disease...
Autores principales: | Bim, Larissa V., Navarro, Fábio C. P., Valente, Flávia O. F., Lima-Junior, José V., Delcelo, Rosana, Dias-da-Silva, Magnus R., Maciel, Rui M. B., Galante, Pedro A. F., Cerutti, Janete M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617568/ https://www.ncbi.nlm.nih.gov/pubmed/31288802 http://dx.doi.org/10.1186/s12920-019-0552-1 |
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