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Frequency and patterns of second-line resistance conferring mutations among MDR-TB isolates resistant to a second-line drug from eSwatini, Somalia and Uganda (2014–2016)
BACKGROUND: Pulmonary tuberculosis is a leading cause of morbidity and mortality in developing countries. Drug resistance, a huge problem in this contagious disease, is driven by point mutations in the Mycobacterium tuberculosis genome however, their frequencies vary geographically and this affects...
Autores principales: | Kateete, David Patrick, Kamulegeya, Rogers, Kigozi, Edgar, Katabazi, Fred Ashaba, Lukoye, Deus, Sebit, Sindani Ireneaus, Abdi, Hergeye, Arube, Peter, Kasule, George William, Musisi, Kenneth, Dlamini, Myalo Glen, Khumalo, Derrick, Joloba, Moses L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617586/ https://www.ncbi.nlm.nih.gov/pubmed/31291943 http://dx.doi.org/10.1186/s12890-019-0891-x |
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