Cargando…

Prescribing pattern of statins for primary prevention of cardiovascular diseases in patients with type 2 diabetes: insights from Ethiopia

OBJECTIVE: Although most clinical practice guidelines endorsed statin use in type 2 diabetes (T2D) patients for reducing cardiovascular diseases (CVD), little is known about statin utilization in case of Ethiopia. Hence, this study was aimed to evaluate prescribing pattern of statins for primary pre...

Descripción completa

Detalles Bibliográficos
Autores principales: Demoz, Gebre Teklemariam, Wahdey, Shishay, Kasahun, Gebremicheal Gebreslassie, Hagazy, Kalay, Kinfe, Daniel Gebrehawaria, Tasew, Hagos, Bahrey, Degena, Niriayo, Yirga Legesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617647/
https://www.ncbi.nlm.nih.gov/pubmed/31288848
http://dx.doi.org/10.1186/s13104-019-4423-9
_version_ 1783433738551558144
author Demoz, Gebre Teklemariam
Wahdey, Shishay
Kasahun, Gebremicheal Gebreslassie
Hagazy, Kalay
Kinfe, Daniel Gebrehawaria
Tasew, Hagos
Bahrey, Degena
Niriayo, Yirga Legesse
author_facet Demoz, Gebre Teklemariam
Wahdey, Shishay
Kasahun, Gebremicheal Gebreslassie
Hagazy, Kalay
Kinfe, Daniel Gebrehawaria
Tasew, Hagos
Bahrey, Degena
Niriayo, Yirga Legesse
author_sort Demoz, Gebre Teklemariam
collection PubMed
description OBJECTIVE: Although most clinical practice guidelines endorsed statin use in type 2 diabetes (T2D) patients for reducing cardiovascular diseases (CVD), little is known about statin utilization in case of Ethiopia. Hence, this study was aimed to evaluate prescribing pattern of statins for primary prevention of CVD in T2D patients. A retrospective study conducted in T2D patients with the age group of 40–75 years. Prescriptions were audited for details of statin use and dose intensity. Descriptive analysis was performed using SPSS version 22.0. RESULTS: We included a total of 323 study subjects. Of those, 55.7% study subjects were found to be received statin for their primary prevention of CVD. Commonly prescribed type of statins was simvastatin (37.2%), atorvastatin (32.8%) and rosuvastatin (15.6%). Low, moderate and high intensive dose of statins were prescribed in 27.8%, 46.1%, and 26.1%, respectively. Of those subjects received statin, 60.6% had on target cholesterol level. Overall, a significant percentage of subjects did not receive their recommended statin for primary prevention of CVD which is below the guidelines’ recommendation. Therefore, adherence to guidelines may help to promote the use of statins for primary prevention of CVD in T2D and advance interventions to improve statin prescribing should be considered. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-019-4423-9) contains supplementary material, which is available to authorized users.
format Online
Article
Text
id pubmed-6617647
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-66176472019-07-18 Prescribing pattern of statins for primary prevention of cardiovascular diseases in patients with type 2 diabetes: insights from Ethiopia Demoz, Gebre Teklemariam Wahdey, Shishay Kasahun, Gebremicheal Gebreslassie Hagazy, Kalay Kinfe, Daniel Gebrehawaria Tasew, Hagos Bahrey, Degena Niriayo, Yirga Legesse BMC Res Notes Research Note OBJECTIVE: Although most clinical practice guidelines endorsed statin use in type 2 diabetes (T2D) patients for reducing cardiovascular diseases (CVD), little is known about statin utilization in case of Ethiopia. Hence, this study was aimed to evaluate prescribing pattern of statins for primary prevention of CVD in T2D patients. A retrospective study conducted in T2D patients with the age group of 40–75 years. Prescriptions were audited for details of statin use and dose intensity. Descriptive analysis was performed using SPSS version 22.0. RESULTS: We included a total of 323 study subjects. Of those, 55.7% study subjects were found to be received statin for their primary prevention of CVD. Commonly prescribed type of statins was simvastatin (37.2%), atorvastatin (32.8%) and rosuvastatin (15.6%). Low, moderate and high intensive dose of statins were prescribed in 27.8%, 46.1%, and 26.1%, respectively. Of those subjects received statin, 60.6% had on target cholesterol level. Overall, a significant percentage of subjects did not receive their recommended statin for primary prevention of CVD which is below the guidelines’ recommendation. Therefore, adherence to guidelines may help to promote the use of statins for primary prevention of CVD in T2D and advance interventions to improve statin prescribing should be considered. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-019-4423-9) contains supplementary material, which is available to authorized users. BioMed Central 2019-07-09 /pmc/articles/PMC6617647/ /pubmed/31288848 http://dx.doi.org/10.1186/s13104-019-4423-9 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Demoz, Gebre Teklemariam
Wahdey, Shishay
Kasahun, Gebremicheal Gebreslassie
Hagazy, Kalay
Kinfe, Daniel Gebrehawaria
Tasew, Hagos
Bahrey, Degena
Niriayo, Yirga Legesse
Prescribing pattern of statins for primary prevention of cardiovascular diseases in patients with type 2 diabetes: insights from Ethiopia
title Prescribing pattern of statins for primary prevention of cardiovascular diseases in patients with type 2 diabetes: insights from Ethiopia
title_full Prescribing pattern of statins for primary prevention of cardiovascular diseases in patients with type 2 diabetes: insights from Ethiopia
title_fullStr Prescribing pattern of statins for primary prevention of cardiovascular diseases in patients with type 2 diabetes: insights from Ethiopia
title_full_unstemmed Prescribing pattern of statins for primary prevention of cardiovascular diseases in patients with type 2 diabetes: insights from Ethiopia
title_short Prescribing pattern of statins for primary prevention of cardiovascular diseases in patients with type 2 diabetes: insights from Ethiopia
title_sort prescribing pattern of statins for primary prevention of cardiovascular diseases in patients with type 2 diabetes: insights from ethiopia
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617647/
https://www.ncbi.nlm.nih.gov/pubmed/31288848
http://dx.doi.org/10.1186/s13104-019-4423-9
work_keys_str_mv AT demozgebreteklemariam prescribingpatternofstatinsforprimarypreventionofcardiovasculardiseasesinpatientswithtype2diabetesinsightsfromethiopia
AT wahdeyshishay prescribingpatternofstatinsforprimarypreventionofcardiovasculardiseasesinpatientswithtype2diabetesinsightsfromethiopia
AT kasahungebremichealgebreslassie prescribingpatternofstatinsforprimarypreventionofcardiovasculardiseasesinpatientswithtype2diabetesinsightsfromethiopia
AT hagazykalay prescribingpatternofstatinsforprimarypreventionofcardiovasculardiseasesinpatientswithtype2diabetesinsightsfromethiopia
AT kinfedanielgebrehawaria prescribingpatternofstatinsforprimarypreventionofcardiovasculardiseasesinpatientswithtype2diabetesinsightsfromethiopia
AT tasewhagos prescribingpatternofstatinsforprimarypreventionofcardiovasculardiseasesinpatientswithtype2diabetesinsightsfromethiopia
AT bahreydegena prescribingpatternofstatinsforprimarypreventionofcardiovasculardiseasesinpatientswithtype2diabetesinsightsfromethiopia
AT niriayoyirgalegesse prescribingpatternofstatinsforprimarypreventionofcardiovasculardiseasesinpatientswithtype2diabetesinsightsfromethiopia