IL-1β receptor antagonist (IL-1Ra) combined with autophagy inducer (TAT-Beclin1) is an effective alternative for attenuating extracellular matrix degradation in rat and human osteoarthritis chondrocytes

BACKGROUND: Autophagy induction is an effective approach for OA therapy. IL-1β is one of the major inflammatory cytokines linked to OA pathological progression, and its receptor blockade interrupts OA cartilage destruction. The objective of this study was to decipher the link between autophagy and r...

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Detalles Bibliográficos
Autores principales: Wang, Fen, Liu, Jijie, Chen, Xiaolei, Zheng, Xinpeng, Qu, Ning, Zhang, Bing, Xia, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617669/
https://www.ncbi.nlm.nih.gov/pubmed/31291980
http://dx.doi.org/10.1186/s13075-019-1952-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617669/
https://www.ncbi.nlm.nih.gov/pubmed/31291980
http://dx.doi.org/10.1186/s13075-019-1952-5

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