Pathological changes are associated with shifts in the employment of synonymous codons at the transcriptome level

BACKGROUND: The usage of different synonymous codons reflects the genome organization and has been connected to parameters such as mRNA abundance and protein folding. It is also been established that mutations targeting specific synonymous codons can trigger disease. RESULTS: We performed a systemat...

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Detalles Bibliográficos
Autores principales: Fornasiero, Eugenio F., Rizzoli, Silvio O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617700/
https://www.ncbi.nlm.nih.gov/pubmed/31288782
http://dx.doi.org/10.1186/s12864-019-5921-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617700/
https://www.ncbi.nlm.nih.gov/pubmed/31288782
http://dx.doi.org/10.1186/s12864-019-5921-9

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