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Pathological changes are associated with shifts in the employment of synonymous codons at the transcriptome level
BACKGROUND: The usage of different synonymous codons reflects the genome organization and has been connected to parameters such as mRNA abundance and protein folding. It is also been established that mutations targeting specific synonymous codons can trigger disease. RESULTS: We performed a systemat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617700/ https://www.ncbi.nlm.nih.gov/pubmed/31288782 http://dx.doi.org/10.1186/s12864-019-5921-9 |