Distinct chromatin structures at the monoamine oxidase‐A promoter correlate with allele‐specific expression in SH‐SY5Y cells

Monoamine oxidase‐A (MAOA) metabolises monoamines and is implicated in the pathophysiology of psychiatric disorders. A polymorphic repetitive DNA domain, termed the uVNTR (upstream variable number tandem repeat), located at the promoter of the MAOA gene is a risk factor for many of these disorders....

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Detalles Bibliográficos
Autores principales: Manca, M., Pessoa, V., Myers, P., Pickles, A., Hill, J., Sharp, H., Murgatroyd, C., Bubb, V. J., Quinn, J. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617726/
https://www.ncbi.nlm.nih.gov/pubmed/29667298
http://dx.doi.org/10.1111/gbb.12483

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