Synthesis, (3)H‐labelling and in vitro evaluation of a substituted dipiperidine alcohol as a potential ligand for chemokine receptor 2

The immune system is implicated in the pathology of neurodegenerative disorders. The C‐C chemokine receptor 2 (CCR2) is one of the key targets involved in the activation of the immune system. A suitable ligand for CCR2 could be a useful tool to study immune activation in central nervous system (CNS)...

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Detalles Bibliográficos
Autores principales: Artelsmair, Markus, Miranda‐Azpiazu, Patricia, Kingston, Lee, Bergare, Jonas, Schou, Magnus, Varrone, Andrea, Elmore, Charles S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617762/
https://www.ncbi.nlm.nih.gov/pubmed/30937946
http://dx.doi.org/10.1002/jlcr.3731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617762/
https://www.ncbi.nlm.nih.gov/pubmed/30937946
http://dx.doi.org/10.1002/jlcr.3731

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