Pilot‐scale process for magnetic bead purification of antibodies directly from non‐clarified CHO cell culture

High capacity magnetic protein A agarose beads, LOABeads PrtA, were used in the development of a new process for affinity purification of monoclonal antibodies (mAbs) from non‐clarified CHO cell broth using a pilot‐scale magnetic separator. The LOABeads had a maximum binding capacity of 65 mg/mL and...

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Detalles Bibliográficos
Autores principales: Brechmann, Nils A., Eriksson, Per‐Olov, Eriksson, Kristofer, Oscarsson, Sven, Buijs, Jos, Shokri, Atefeh, Hjälm, Göran, Chotteau, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617771/
https://www.ncbi.nlm.nih.gov/pubmed/30629859
http://dx.doi.org/10.1002/btpr.2775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617771/
https://www.ncbi.nlm.nih.gov/pubmed/30629859
http://dx.doi.org/10.1002/btpr.2775

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