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The microbiota–gut–brain axis: A promising avenue to foster healthy developmental outcomes

Fostering healthy developmental growth in the first years of life is associated with numerous favorable cognitive, social, and economic outcomes. Funding and promoting research aimed at identifying potential targets for early intervention should be a top priority for lawmakers and funders. One promi...

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Detalles Bibliográficos
Autores principales: Brett, Bonnie E., de Weerth, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617777/
https://www.ncbi.nlm.nih.gov/pubmed/30640409
http://dx.doi.org/10.1002/dev.21824
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author Brett, Bonnie E.
de Weerth, Carolina
author_facet Brett, Bonnie E.
de Weerth, Carolina
author_sort Brett, Bonnie E.
collection PubMed
description Fostering healthy developmental growth in the first years of life is associated with numerous favorable cognitive, social, and economic outcomes. Funding and promoting research aimed at identifying potential targets for early intervention should be a top priority for lawmakers and funders. One promising avenue of research and potential early intervention is the microbiota–gut–brain axis. In this report, we briefly examine the role of the gut microbiota in human life, focusing on links with health, cognition, and behavior. We then discuss the development of the gut microbiota and the critical early window in which colonization occurs. Then, we review current nonnutritive means of influencing the gut microbiota in early life. Finally, we discuss the implications this work has for early intervention in low‐income communities and end with recommendations regarding further research and research funding priorities.
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spelling pubmed-66177772019-07-22 The microbiota–gut–brain axis: A promising avenue to foster healthy developmental outcomes Brett, Bonnie E. de Weerth, Carolina Dev Psychobiol Special Issue Fostering healthy developmental growth in the first years of life is associated with numerous favorable cognitive, social, and economic outcomes. Funding and promoting research aimed at identifying potential targets for early intervention should be a top priority for lawmakers and funders. One promising avenue of research and potential early intervention is the microbiota–gut–brain axis. In this report, we briefly examine the role of the gut microbiota in human life, focusing on links with health, cognition, and behavior. We then discuss the development of the gut microbiota and the critical early window in which colonization occurs. Then, we review current nonnutritive means of influencing the gut microbiota in early life. Finally, we discuss the implications this work has for early intervention in low‐income communities and end with recommendations regarding further research and research funding priorities. John Wiley and Sons Inc. 2019-01-14 2019-07 /pmc/articles/PMC6617777/ /pubmed/30640409 http://dx.doi.org/10.1002/dev.21824 Text en © 2019 The Authors. Developmental Psychobiology Published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Special Issue
Brett, Bonnie E.
de Weerth, Carolina
The microbiota–gut–brain axis: A promising avenue to foster healthy developmental outcomes
title The microbiota–gut–brain axis: A promising avenue to foster healthy developmental outcomes
title_full The microbiota–gut–brain axis: A promising avenue to foster healthy developmental outcomes
title_fullStr The microbiota–gut–brain axis: A promising avenue to foster healthy developmental outcomes
title_full_unstemmed The microbiota–gut–brain axis: A promising avenue to foster healthy developmental outcomes
title_short The microbiota–gut–brain axis: A promising avenue to foster healthy developmental outcomes
title_sort microbiota–gut–brain axis: a promising avenue to foster healthy developmental outcomes
topic Special Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617777/
https://www.ncbi.nlm.nih.gov/pubmed/30640409
http://dx.doi.org/10.1002/dev.21824
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