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Five‐minute whole‐heart coronary MRA with sub‐millimeter isotropic resolution, 100% respiratory scan efficiency, and 3D‐PROST reconstruction

PURPOSE: To enable whole‐heart 3D coronary magnetic resonance angiography (CMRA) with isotropic sub‐millimeter resolution in a clinically feasible scan time by combining respiratory motion correction with highly accelerated variable density sampling in concert with a novel 3D patch‐based undersample...

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Autores principales: Bustin, Aurélien, Ginami, Giulia, Cruz, Gastão, Correia, Teresa, Ismail, Tevfik F., Rashid, Imran, Neji, Radhouene, Botnar, René M., Prieto, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617822/
https://www.ncbi.nlm.nih.gov/pubmed/30058252
http://dx.doi.org/10.1002/mrm.27354
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author Bustin, Aurélien
Ginami, Giulia
Cruz, Gastão
Correia, Teresa
Ismail, Tevfik F.
Rashid, Imran
Neji, Radhouene
Botnar, René M.
Prieto, Claudia
author_facet Bustin, Aurélien
Ginami, Giulia
Cruz, Gastão
Correia, Teresa
Ismail, Tevfik F.
Rashid, Imran
Neji, Radhouene
Botnar, René M.
Prieto, Claudia
author_sort Bustin, Aurélien
collection PubMed
description PURPOSE: To enable whole‐heart 3D coronary magnetic resonance angiography (CMRA) with isotropic sub‐millimeter resolution in a clinically feasible scan time by combining respiratory motion correction with highly accelerated variable density sampling in concert with a novel 3D patch‐based undersampled reconstruction (3D‐PROST). METHODS: An undersampled variable density spiral‐like Cartesian trajectory was combined with 2D image‐based navigators to achieve 100% respiratory efficiency and predictable scan time. 3D‐PROST reconstruction integrates structural information from 3D patch neighborhoods through sparse representation, thereby exploiting the redundancy of the 3D anatomy of the coronary arteries in an efficient low‐rank formulation. The proposed framework was evaluated in a static resolution phantom and in 10 healthy subjects with isotropic resolutions of 1.2 mm(3) and 0.9 mm(3) and undersampling factors of ×5 and ×9. 3D‐PROST was compared against fully sampled (1.2 mm(3) only), conventional parallel imaging, and compressed sensing reconstructions. RESULTS: Phantom and in vivo (1.2 mm(3)) reconstructions were in excellent agreement with the reference fully sampled image. In vivo average acquisition times (min:s) were 7:57 ± 1:18 (×5) and 4:35 ± 0:44 (×9) for 0.9 mm(3) resolution. Sub‐millimeter 3D‐PROST resulted in excellent depiction of the left and right coronary arteries including small branch vessels, leading to further improvements in vessel sharpness and visible vessel length in comparison with conventional reconstruction techniques. Image quality rated by 2 experts demonstrated that 3D‐PROST provides good image quality and is robust even at high acceleration factors. CONCLUSION: The proposed approach enables free‐breathing whole‐heart 3D CMRA with isotropic sub‐millimeter resolution in <5 min and achieves improved coronary artery visualization in a short and predictable scan time.
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spelling pubmed-66178222019-07-22 Five‐minute whole‐heart coronary MRA with sub‐millimeter isotropic resolution, 100% respiratory scan efficiency, and 3D‐PROST reconstruction Bustin, Aurélien Ginami, Giulia Cruz, Gastão Correia, Teresa Ismail, Tevfik F. Rashid, Imran Neji, Radhouene Botnar, René M. Prieto, Claudia Magn Reson Med Full Papers—Imaging Methodology PURPOSE: To enable whole‐heart 3D coronary magnetic resonance angiography (CMRA) with isotropic sub‐millimeter resolution in a clinically feasible scan time by combining respiratory motion correction with highly accelerated variable density sampling in concert with a novel 3D patch‐based undersampled reconstruction (3D‐PROST). METHODS: An undersampled variable density spiral‐like Cartesian trajectory was combined with 2D image‐based navigators to achieve 100% respiratory efficiency and predictable scan time. 3D‐PROST reconstruction integrates structural information from 3D patch neighborhoods through sparse representation, thereby exploiting the redundancy of the 3D anatomy of the coronary arteries in an efficient low‐rank formulation. The proposed framework was evaluated in a static resolution phantom and in 10 healthy subjects with isotropic resolutions of 1.2 mm(3) and 0.9 mm(3) and undersampling factors of ×5 and ×9. 3D‐PROST was compared against fully sampled (1.2 mm(3) only), conventional parallel imaging, and compressed sensing reconstructions. RESULTS: Phantom and in vivo (1.2 mm(3)) reconstructions were in excellent agreement with the reference fully sampled image. In vivo average acquisition times (min:s) were 7:57 ± 1:18 (×5) and 4:35 ± 0:44 (×9) for 0.9 mm(3) resolution. Sub‐millimeter 3D‐PROST resulted in excellent depiction of the left and right coronary arteries including small branch vessels, leading to further improvements in vessel sharpness and visible vessel length in comparison with conventional reconstruction techniques. Image quality rated by 2 experts demonstrated that 3D‐PROST provides good image quality and is robust even at high acceleration factors. CONCLUSION: The proposed approach enables free‐breathing whole‐heart 3D CMRA with isotropic sub‐millimeter resolution in <5 min and achieves improved coronary artery visualization in a short and predictable scan time. John Wiley and Sons Inc. 2018-07-29 2019-01 /pmc/articles/PMC6617822/ /pubmed/30058252 http://dx.doi.org/10.1002/mrm.27354 Text en © 2018 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Full Papers—Imaging Methodology
Bustin, Aurélien
Ginami, Giulia
Cruz, Gastão
Correia, Teresa
Ismail, Tevfik F.
Rashid, Imran
Neji, Radhouene
Botnar, René M.
Prieto, Claudia
Five‐minute whole‐heart coronary MRA with sub‐millimeter isotropic resolution, 100% respiratory scan efficiency, and 3D‐PROST reconstruction
title Five‐minute whole‐heart coronary MRA with sub‐millimeter isotropic resolution, 100% respiratory scan efficiency, and 3D‐PROST reconstruction
title_full Five‐minute whole‐heart coronary MRA with sub‐millimeter isotropic resolution, 100% respiratory scan efficiency, and 3D‐PROST reconstruction
title_fullStr Five‐minute whole‐heart coronary MRA with sub‐millimeter isotropic resolution, 100% respiratory scan efficiency, and 3D‐PROST reconstruction
title_full_unstemmed Five‐minute whole‐heart coronary MRA with sub‐millimeter isotropic resolution, 100% respiratory scan efficiency, and 3D‐PROST reconstruction
title_short Five‐minute whole‐heart coronary MRA with sub‐millimeter isotropic resolution, 100% respiratory scan efficiency, and 3D‐PROST reconstruction
title_sort five‐minute whole‐heart coronary mra with sub‐millimeter isotropic resolution, 100% respiratory scan efficiency, and 3d‐prost reconstruction
topic Full Papers—Imaging Methodology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617822/
https://www.ncbi.nlm.nih.gov/pubmed/30058252
http://dx.doi.org/10.1002/mrm.27354
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