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Glibenclamide in aneurysmatic subarachnoid hemorrhage (GASH): study protocol for a randomized controlled trial

BACKGROUND: Recent findings on the benefits of glibenclamide as a neuroprotective drug have started a new era for prospective studies on sulfonylureas. The effect of glibenclamide blocking the Sur1-Trpm4 channel was examined in models of subarachnoid hemorrhage and stroke, with findings of significa...

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Detalles Bibliográficos
Autores principales: da Costa, Bruno Braga Sisnando, Windlin, Isabela Costola, Koterba, Edwin, Yamaki, Vitor Nagai, Rabelo, Nícollas Nunes, Solla, Davi Jorge Fontoura, Teixeira, Manoel Jacobsen, Figueiredo, Eberval Gadelha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617901/
https://www.ncbi.nlm.nih.gov/pubmed/31288831
http://dx.doi.org/10.1186/s13063-019-3517-y