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Glibenclamide in aneurysmatic subarachnoid hemorrhage (GASH): study protocol for a randomized controlled trial
BACKGROUND: Recent findings on the benefits of glibenclamide as a neuroprotective drug have started a new era for prospective studies on sulfonylureas. The effect of glibenclamide blocking the Sur1-Trpm4 channel was examined in models of subarachnoid hemorrhage and stroke, with findings of significa...
Autores principales: | da Costa, Bruno Braga Sisnando, Windlin, Isabela Costola, Koterba, Edwin, Yamaki, Vitor Nagai, Rabelo, Nícollas Nunes, Solla, Davi Jorge Fontoura, Teixeira, Manoel Jacobsen, Figueiredo, Eberval Gadelha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617901/ https://www.ncbi.nlm.nih.gov/pubmed/31288831 http://dx.doi.org/10.1186/s13063-019-3517-y |
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