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Contributions of T cell dysfunction to the resistance against anti-PD-1 therapy in oral carcinogenesis

BACKGROUND: Programmed death 1 (PD-1) blockade has great effect in the prevention of oral precancerous lesions, but the drug resistance has also been observed. The determinants of immune resistance during the malignant transformation are poorly understood. METHODS: Anti-PD-1 antibody was administere...

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Detalles Bibliográficos
Autores principales:	Wen, Liling, Lu, Huanzi, Li, Qiusheng, Li, Qunxing, Wen, Shuqiong, Wang, Dikan, Wang, Xi, Fang, Juan, Cui, Jun, Cheng, Bin, Wang, Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617956/ https://www.ncbi.nlm.nih.gov/pubmed/31291983 http://dx.doi.org/10.1186/s13046-019-1185-0

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