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Targeted therapy of the AKT kinase inhibits esophageal squamous cell carcinoma growth in vitro and in vivo

Esophageal cancer, a leading cause of cancer death worldwide, is associated with abnormal activation of the AKT signaling pathway. Xanthohumol, a prenylated flavonoid tested in clinical trials, is reported to exert anti‐diabetes, anti‐inflammation and anticancer activities. However, the mechanisms u...

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Detalles Bibliográficos
Autores principales:	Liu, Xuejiao, Song, Mengqiu, Wang, Penglei, Zhao, Ran, Chen, Hanyong, Zhang, Man, Shi, Yuanyuan, Liu, Kangdong, Liu, Fangfang, Yang, Ran, Li, Enmin, Bode, Ann M., Dong, Zigang, Lee, Mee‐Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2019
Materias:	Cancer Therapy and Prevention
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618024/ https://www.ncbi.nlm.nih.gov/pubmed/30887517 http://dx.doi.org/10.1002/ijc.32285

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