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Dexmedetomidine protects PC12 cells from lidocaine-induced cytotoxicity via downregulation of Stathmin 1

Background: Understanding of lidocaine-induced neurotoxicity is not complete, resulting in the unsuccessful treatment in some clinical settings. Dexmedetomidine (DEX) has been shown to alleviate lidocaine-induced neurotoxicity in our previous cell model. However, the rationale for DEX combined with...

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Detalles Bibliográficos
Autores principales: Tan, Yonghong, Bi, Xiaobao, Wang, Qiong, Li, Yu, Zhang, Na, Lao, Jianxin, Liu, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618032/
https://www.ncbi.nlm.nih.gov/pubmed/31308624
http://dx.doi.org/10.2147/DDDT.S199572