Cargando…

IL‐8 and CXCR1 expression is associated with cancer stem cell‐like properties of clear cell renal cancer

Recent studies suggest that clear cell renal cell carcinoma (ccRCC) possesses a rare population of cancer stem cells (CSCs) that might contribute to tumor heterogeneity, metastasis and therapeutic resistance. Nevertheless, their relevance for renal cancer is still unclear. In this study, we successf...

Descripción completa

Detalles Bibliográficos
Autores principales:	Corrò, Claudia, Healy, Marc E, Engler, Stefanie, Bodenmiller, Bernd, Li, Zhe, Schraml, Peter, Weber, Achim, Frew, Ian J, Rechsteiner, Markus, Moch, Holger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2019
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618115/ https://www.ncbi.nlm.nih.gov/pubmed/30883740 http://dx.doi.org/10.1002/path.5267

Ejemplares similares

VHL missense mutations in the p53 binding domain show different effects on p53 signaling and HIFα degradation in clear cell renal cell carcinoma
por: Razafinjatovo, Caroline Fanja, et al.
Publicado: (2016)

Multiplex imaging of breast cancer lymph node metastases identifies prognostic single-cell populations independent of clinical classifiers
por: Fischer, Jana Raja, et al.
Publicado: (2023)

Biomarker discovery for renal cancer stem cells
por: Corrò, Claudia, et al.
Publicado: (2018)

Expression and Mutation Patterns of PBRM1, BAP1 and SETD2 Mirror Specific Evolutionary Subtypes in Clear Cell Renal Cell Carcinoma()
por: Bihr, Svenja, et al.
Publicado: (2019)

Scavenger receptor BI promotes cytoplasmic accumulation of lipoproteins in clear-cell renal cell carcinoma
por: Velagapudi, Srividya, et al.
Publicado: (2018)

Three-dimensional imaging mass cytometry for highly multiplexed molecular and cellular mapping of tissues and the tumor microenvironment
por: Kuett, Laura, et al.
Publicado: (2022)

Spatial Distribution of Private Gene Mutations in Clear Cell Renal Cell Carcinoma
por: Moore, Ariane L., et al.
Publicado: (2021)

Characterization of VHL missense mutations in sporadic clear cell renal cell carcinoma: hotspots, affected binding domains, functional impact on pVHL and therapeutic relevance
por: Razafinjatovo, Caroline, et al.
Publicado: (2016)

Tumor-associated macrophages subvert T-cell function and correlate with reduced survival in clear cell renal cell carcinoma
por: Dannenmann, Stefanie Regine, et al.
Publicado: (2013)

An Immune Atlas of Clear Cell Renal Cell Carcinoma
por: Chevrier, Stéphane, et al.
Publicado: (2017)

Combined Vhl, Trp53 and Rb1 mutation causes clear cell renal cell carcinoma in mice
por: Harlander, Sabine, et al.
Publicado: (2017)

Cytoplasmic ADP-ribosylation levels correlate with markers of patient outcome in distinct human cancers
por: Aimi, Fabio, et al.
Publicado: (2021)

Somatic BRCA1 mutations in clinically sporadic breast cancer with medullary histological features
por: Rechsteiner, Markus, et al.
Publicado: (2018)

ROS1 genomic rearrangements are rare actionable drivers in microsatellite stable colorectal cancer
por: Akhoundova, Dilara, et al.
Publicado: (2022)

Optimizing multiplexed imaging experimental design through tissue spatial segregation estimation
por: Bost, Pierre, et al.
Publicado: (2022)

Cancer Sample Biobanking at the Next Level: Combining Tissue With Living Cell Repositories to Promote Precision Medicine
por: Bolck, Hella A., et al.
Publicado: (2019)

Functional characterization of BC039389-GATM and KLK4-KRSP1 chimeric read-through transcripts which are up-regulated in renal cell cancer
por: Pflueger, Dorothee, et al.
Publicado: (2015)

Automated Assessment of β-Cell Area and Density per Islet and Patient Using TMEM27 and BACE2 Immunofluorescence Staining in Human Pancreatic β-Cells
por: Rechsteiner, Markus P., et al.
Publicado: (2014)

Multielement Z-tag imaging by X-ray fluorescence microscopy for next-generation multiplex imaging
por: Strotton, Merrick, et al.
Publicado: (2023)

Next Generation Sequencing of Reactive Stroma and Residual Breast Cancer Cells in Tumor Bed after Neoadjuvant Chemotherapy
por: Varga, Zsuzsanna, et al.
Publicado: (2022)

MiR-99b-5p expression and response to tyrosine kinase inhibitor treatment in clear cell renal cell carcinoma patients
por: Lukamowicz-Rajska, Magdalena, et al.
Publicado: (2016)

Liquid Biopsies in Renal Cell Carcinoma—Recent Advances and Promising New Technologies for the Early Detection of Metastatic Disease
por: Lakshminarayanan, Harini, et al.
Publicado: (2020)

Liver cancer with concomitant TP53 and CTNNB1 mutations: a case report
por: Friemel, Juliane, et al.
Publicado: (2016)

Simultaneous Multiplexed Imaging of mRNA and Proteins with Subcellular Resolution in Breast Cancer Tissue Samples by Mass Cytometry
por: Schulz, Daniel, et al.
Publicado: (2018)

Simultaneous Multiplexed Imaging of mRNA and Proteins with Subcellular Resolution in Breast Cancer Tissue Samples by Mass Cytometry
por: Schulz, Daniel, et al.
Publicado: (2018)

Fluid shear stress-induced IL-8/CXCR signaling in human ovarian cancer cells
por: Sun, Lei, et al.
Publicado: (2019)

Profiling Cell Signaling Networks at Single-cell Resolution
por: Lun, Xiao-Kang, et al.
Publicado: (2020)

Homogeneous MGMT Immunoreactivity Correlates with an Unmethylated MGMT Promoter Status in Brain Metastases of Various Solid Tumors
por: Ingold, Barbara, et al.
Publicado: (2009)

Acquired resistance to anti-PD1 therapy in patients with NSCLC associates with immunosuppressive T cell phenotype
por: Hiltbrunner, Stefanie, et al.
Publicado: (2023)

Compensation of Signal Spillover in Suspension and Imaging Mass Cytometry
por: Chevrier, Stéphane, et al.
Publicado: (2018)

Induction of cathepsin B by the CXCR3 chemokines CXCL9 and CXCL10 in human breast cancer cells
por: Bronger, Holger, et al.
Publicado: (2017)

p53 suppresses type II endometrial carcinomas in mice and governs endometrial tumour aggressiveness in humans
por: Wild, Peter J, et al.
Publicado: (2012)

Detailed simulation of cancer exome sequencing data reveals differences and common limitations of variant callers
por: Hofmann, Ariane L., et al.
Publicado: (2017)

Combined mutation of Vhl and Trp53 causes renal cysts and tumours in mice
por: Albers, Joachim, et al.
Publicado: (2013)

CXCR4 antagonists suppress small cell lung cancer progression
por: Taromi, Sanaz, et al.
Publicado: (2016)

FMNL1 Exhibits Pro-Metastatic Activity via CXCR2 in Clear Cell Renal Cell Carcinoma
por: Zhang, Mei-Fang, et al.
Publicado: (2020)

Characterization of the Prognostic Values of the CXCR1-7 in Clear Cell Renal Cell Carcinoma (ccRCC) Microenvironment
por: Wu, Zhulin, et al.
Publicado: (2020)

Loss of CDKN1A mRNA and Protein Expression Are Independent Predictors of Poor Outcome in Chromophobe Renal Cell Carcinoma Patients
por: Ohashi, Riuko, et al.
Publicado: (2020)

Altered cytoplasmic and nuclear ADP‐ribosylation levels analyzed with an improved ADP‐ribose binder are a prognostic factor in renal cell carcinoma
por: Schraml, Peter, et al.
Publicado: (2023)

MALDI Mass Spectrometry Imaging—Prognostic Pathways and Metabolites for Renal Cell Carcinomas
por: Erlmeier, Franziska, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_d072iqjf6jlmu85shfbq53h10s