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Optimised Synthesis of the Bacterial Magic Spot (p)ppGpp Chemosensor PyDPA
Guanosine penta‐ or tetraphosphate (pppGpp or ppGpp, respectively) is a nucleotide signalling molecule with a marked effect on bacterial physiology during stress. Its accumulation slows down cell metabolism and replication, supposedly leading to the formation of the antibiotic‐tolerant persister phe...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618120/ https://www.ncbi.nlm.nih.gov/pubmed/30843657 http://dx.doi.org/10.1002/cbic.201900013 |