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Biologic therapy for acrodermatitis continua of Hallopeau: Successful treatment with secukinumab and review of the literature
Acrodermatitis continua of Hallopeau (ACH) is a rare pustular psoriasis variant refractory to many conventional treatments. We report the successful treatment with secukinumab of a patient with a long history of ACH with marked onychodystrophy with frank pustulosis on the nail bed and with accompany...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618131/ https://www.ncbi.nlm.nih.gov/pubmed/30969010 http://dx.doi.org/10.1111/dth.12899 |
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author | Galluzzo, Marco D'Adamio, Simone Teoli, Miriam Bianchi, Luca Talamonti, Marina |
author_facet | Galluzzo, Marco D'Adamio, Simone Teoli, Miriam Bianchi, Luca Talamonti, Marina |
author_sort | Galluzzo, Marco |
collection | PubMed |
description | Acrodermatitis continua of Hallopeau (ACH) is a rare pustular psoriasis variant refractory to many conventional treatments. We report the successful treatment with secukinumab of a patient with a long history of ACH with marked onychodystrophy with frank pustulosis on the nail bed and with accompanying arthritis. Blockade of the IL‐17 receptor A has shown promise in the treatment of psoriatic erythroderma and generalized pustular psoriasis not responsive to conventional treatment. A rapid response was observed in our patient, in both skin lesions and arthritic symptoms, underlining the ability of secukinumab to improve symptoms beyond those of plaque psoriasis. |
format | Online Article Text |
id | pubmed-6618131 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley & Sons, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-66181312019-07-22 Biologic therapy for acrodermatitis continua of Hallopeau: Successful treatment with secukinumab and review of the literature Galluzzo, Marco D'Adamio, Simone Teoli, Miriam Bianchi, Luca Talamonti, Marina Dermatol Ther Therapeutic Hotline: Short Papers Acrodermatitis continua of Hallopeau (ACH) is a rare pustular psoriasis variant refractory to many conventional treatments. We report the successful treatment with secukinumab of a patient with a long history of ACH with marked onychodystrophy with frank pustulosis on the nail bed and with accompanying arthritis. Blockade of the IL‐17 receptor A has shown promise in the treatment of psoriatic erythroderma and generalized pustular psoriasis not responsive to conventional treatment. A rapid response was observed in our patient, in both skin lesions and arthritic symptoms, underlining the ability of secukinumab to improve symptoms beyond those of plaque psoriasis. John Wiley & Sons, Inc. 2019-04-29 2019 /pmc/articles/PMC6618131/ /pubmed/30969010 http://dx.doi.org/10.1111/dth.12899 Text en © 2019 The Authors. Dermatologic Therapy published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Therapeutic Hotline: Short Papers Galluzzo, Marco D'Adamio, Simone Teoli, Miriam Bianchi, Luca Talamonti, Marina Biologic therapy for acrodermatitis continua of Hallopeau: Successful treatment with secukinumab and review of the literature |
title | Biologic therapy for acrodermatitis continua of Hallopeau: Successful treatment with secukinumab and review of the literature |
title_full | Biologic therapy for acrodermatitis continua of Hallopeau: Successful treatment with secukinumab and review of the literature |
title_fullStr | Biologic therapy for acrodermatitis continua of Hallopeau: Successful treatment with secukinumab and review of the literature |
title_full_unstemmed | Biologic therapy for acrodermatitis continua of Hallopeau: Successful treatment with secukinumab and review of the literature |
title_short | Biologic therapy for acrodermatitis continua of Hallopeau: Successful treatment with secukinumab and review of the literature |
title_sort | biologic therapy for acrodermatitis continua of hallopeau: successful treatment with secukinumab and review of the literature |
topic | Therapeutic Hotline: Short Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618131/ https://www.ncbi.nlm.nih.gov/pubmed/30969010 http://dx.doi.org/10.1111/dth.12899 |
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