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Genetic risk of dementia mitigated by cognitive reserve: A cohort study

OBJECTIVE: We investigated whether cognitive reserve modifies the risk of dementia attributable to apolipoprotein ε4 (APOE‐ε4), a well‐known genetic risk factor for dementia. METHODS: We followed 2,556 cognitively intact participants aged ≥60 years from the ongoing prospective community‐based Swedis...

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Detalles Bibliográficos
Autores principales: Dekhtyar, Serhiy, Marseglia, Anna, Xu, Weili, Darin‐Mattsson, Alexander, Wang, Hui‐Xin, Fratiglioni, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618249/
https://www.ncbi.nlm.nih.gov/pubmed/31066941
http://dx.doi.org/10.1002/ana.25501