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Cerebrospinal fluid flow dynamics in Huntington's disease evaluated by phase contrast MRI

Multiple targeted therapeutics for Huntington's disease are now in clinical trials, including intrathecally delivered compounds. Previous research suggests that CSF dynamics may be altered in Huntington's disease, which could be of paramount relevance to intrathecal drug delivery to the br...

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Detalles Bibliográficos
Autores principales: Rodrigues, Filipe B., Byrne, Lauren M., De Vita, Enrico, Johnson, Eileanoir B., Hobbs, Nicola Z., Thornton, John S., Scahill, Rachael I., Wild, Edward J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618296/
https://www.ncbi.nlm.nih.gov/pubmed/30687961
http://dx.doi.org/10.1111/ejn.14356