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Divergent SATB1 expression across human life span and tissue compartments

Special AT‐rich binding protein‐1 (SATB1) is a global chromatin organizer capable of activating or repressing gene transcription in mice and humans. The role of SATB1 is pivotal for T‐cell development, with SATB1‐knockout mice being neonatally lethal, although the exact mechanism is unknown. Moreove...

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Detalles Bibliográficos
Autores principales: Nüssing, Simone, Koay, Hui‐Fern, Sant, Sneha, Loudovaris, Thomas, Mannering, Stuart I, Lappas, Martha, d′Udekem, Yves, Konstantinov, Igor E, Berzins, Stuart P, Rimmelzwaan, Guus F, Turner, Stephen J, Clemens, E Bridie, Godfrey, Dale I, Nguyen, Thi HO, Kedzierska, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618325/
https://www.ncbi.nlm.nih.gov/pubmed/30803026
http://dx.doi.org/10.1111/imcb.12233