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Recombinant BCG With Bacterial Signaling Molecule Cyclic di-AMP as Endogenous Adjuvant Induces Elevated Immune Responses After Mycobacterium tuberculosis Infection

Bacillus Calmette-Guerin (BCG) is a live attenuated vaccine against tuberculosis (TB) and remains the most commonly used vaccine worldwide. However, BCG has varied protective efficiency in adults and has safety concerns in immunocompromised population. Thus, effective vaccines are necessary for prev...

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Detalles Bibliográficos
Autores principales:	Ning, Huanhuan, Wang, Lifei, Zhou, Jie, Lu, Yanzhi, Kang, Jian, Ding, Tianbing, Shen, Lixin, Xu, Zhikai, Bai, Yinlan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618344/ https://www.ncbi.nlm.nih.gov/pubmed/31333655 http://dx.doi.org/10.3389/fimmu.2019.01519

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