Rhein sensitizes human colorectal cancer cells to EGFR inhibitors by inhibiting STAT3 pathway

BACKGROUND: Activation of epidermal growth factor receptor (EGFR) has been reported in a variety of cancer types, including colorectal cancer (CRC), and represents a potential chemotherapeutic drug target. EGFR tyrosine kinase inhibitors (EGFR-TKIs) have been increasingly applied in the clinical tre...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhuang, Yan, Bai, Ying, Hu, Yan, Guo, Yueqin, Xu, Lingyuan, Hu, Wanle, Yang, Lehe, Zhao, Chengguang, Li, Xiaokun, Zhao, Haiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618855/
https://www.ncbi.nlm.nih.gov/pubmed/31308698
http://dx.doi.org/10.2147/OTT.S206833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618855/
https://www.ncbi.nlm.nih.gov/pubmed/31308698
http://dx.doi.org/10.2147/OTT.S206833

Ejemplares similares