Cargando…
Rhein sensitizes human colorectal cancer cells to EGFR inhibitors by inhibiting STAT3 pathway
BACKGROUND: Activation of epidermal growth factor receptor (EGFR) has been reported in a variety of cancer types, including colorectal cancer (CRC), and represents a potential chemotherapeutic drug target. EGFR tyrosine kinase inhibitors (EGFR-TKIs) have been increasingly applied in the clinical tre...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618855/ https://www.ncbi.nlm.nih.gov/pubmed/31308698 http://dx.doi.org/10.2147/OTT.S206833 |