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Automatic mapping of atrial fiber orientations for patient‐specific modeling of cardiac electromechanics using image registration
Knowledge of appropriate local fiber architecture is necessary to simulate patient‐specific electromechanics in the human heart. However, it is not yet possible to reliably measure in vivo fiber directions especially in human atria. Thus, we present a method that defines the fiber architecture in ar...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619047/ https://www.ncbi.nlm.nih.gov/pubmed/30829001 http://dx.doi.org/10.1002/cnm.3190 |
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author | Hoermann, Julia M. Pfaller, Martin R. Avena, Linda Bertoglio, Cristóbal Wall, Wolfgang A. |
author_facet | Hoermann, Julia M. Pfaller, Martin R. Avena, Linda Bertoglio, Cristóbal Wall, Wolfgang A. |
author_sort | Hoermann, Julia M. |
collection | PubMed |
description | Knowledge of appropriate local fiber architecture is necessary to simulate patient‐specific electromechanics in the human heart. However, it is not yet possible to reliably measure in vivo fiber directions especially in human atria. Thus, we present a method that defines the fiber architecture in arbitrarily shaped atria using image registration and reorientation methods based on atlas atria with fibers predefined from detailed histological observations. Thereby, it is possible to generate detailed fiber families in every new patient‐specific geometry in an automated, time‐efficient process. We demonstrate the good performance of the image registration and fiber definition on 10 differently shaped human atria. Additionally, we show that characteristics of the electrophysiological activation pattern that appear in the atlas atria also appear in the patients' atria. We arrive to analogous conclusions for coupled electro‐mechano‐hemodynamical computations. |
format | Online Article Text |
id | pubmed-6619047 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-66190472019-07-22 Automatic mapping of atrial fiber orientations for patient‐specific modeling of cardiac electromechanics using image registration Hoermann, Julia M. Pfaller, Martin R. Avena, Linda Bertoglio, Cristóbal Wall, Wolfgang A. Int J Numer Method Biomed Eng Research Article ‐ Fundamental Knowledge of appropriate local fiber architecture is necessary to simulate patient‐specific electromechanics in the human heart. However, it is not yet possible to reliably measure in vivo fiber directions especially in human atria. Thus, we present a method that defines the fiber architecture in arbitrarily shaped atria using image registration and reorientation methods based on atlas atria with fibers predefined from detailed histological observations. Thereby, it is possible to generate detailed fiber families in every new patient‐specific geometry in an automated, time‐efficient process. We demonstrate the good performance of the image registration and fiber definition on 10 differently shaped human atria. Additionally, we show that characteristics of the electrophysiological activation pattern that appear in the atlas atria also appear in the patients' atria. We arrive to analogous conclusions for coupled electro‐mechano‐hemodynamical computations. John Wiley and Sons Inc. 2019-03-14 2019-06 /pmc/articles/PMC6619047/ /pubmed/30829001 http://dx.doi.org/10.1002/cnm.3190 Text en © 2019 The Authors International Journal for Numerical Methods in Biomedical Engineering Published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article ‐ Fundamental Hoermann, Julia M. Pfaller, Martin R. Avena, Linda Bertoglio, Cristóbal Wall, Wolfgang A. Automatic mapping of atrial fiber orientations for patient‐specific modeling of cardiac electromechanics using image registration |
title | Automatic mapping of atrial fiber orientations for patient‐specific modeling of cardiac electromechanics using image registration |
title_full | Automatic mapping of atrial fiber orientations for patient‐specific modeling of cardiac electromechanics using image registration |
title_fullStr | Automatic mapping of atrial fiber orientations for patient‐specific modeling of cardiac electromechanics using image registration |
title_full_unstemmed | Automatic mapping of atrial fiber orientations for patient‐specific modeling of cardiac electromechanics using image registration |
title_short | Automatic mapping of atrial fiber orientations for patient‐specific modeling of cardiac electromechanics using image registration |
title_sort | automatic mapping of atrial fiber orientations for patient‐specific modeling of cardiac electromechanics using image registration |
topic | Research Article ‐ Fundamental |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619047/ https://www.ncbi.nlm.nih.gov/pubmed/30829001 http://dx.doi.org/10.1002/cnm.3190 |
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