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Experimental pK (a) Value Determination of All Ionizable Groups of a Hyperstable Protein
Electrostatic interactions significantly contribute to the stability and function of proteins. The stabilizing or destabilizing effect of local charge is reflected in the perturbation of the pK (a) value of an ionizable group from the intrinsic pK (a) value. Herein, the charge network of a hyperstab...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619245/ https://www.ncbi.nlm.nih.gov/pubmed/30511779 http://dx.doi.org/10.1002/cbic.201800628 |