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Impact of community based screening for hypertension on blood pressure after two years: regression discontinuity analysis in a national cohort of older adults in China

OBJECTIVE: To estimate the causal impact of community based blood pressure screening on subsequent blood pressure levels among older adults in China. DESIGN: Regression discontinuity analysis using data from a national cohort study. SETTING: 2011-12 and 2014 waves of the Chinese Longitudinal Healthy...

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Autores principales: Chen, Simiao, Sudharsanan, Nikkil, Huang, Feng, Liu, Yuanli, Geldsetzer, Pascal, Bärnighausen, Till
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619453/
https://www.ncbi.nlm.nih.gov/pubmed/31296584
http://dx.doi.org/10.1136/bmj.l4064
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author Chen, Simiao
Sudharsanan, Nikkil
Huang, Feng
Liu, Yuanli
Geldsetzer, Pascal
Bärnighausen, Till
author_facet Chen, Simiao
Sudharsanan, Nikkil
Huang, Feng
Liu, Yuanli
Geldsetzer, Pascal
Bärnighausen, Till
author_sort Chen, Simiao
collection PubMed
description OBJECTIVE: To estimate the causal impact of community based blood pressure screening on subsequent blood pressure levels among older adults in China. DESIGN: Regression discontinuity analysis using data from a national cohort study. SETTING: 2011-12 and 2014 waves of the Chinese Longitudinal Healthy Longevity Survey, a national cohort of older adults in China. PARTICIPANTS: 3899 older adults who had previously undiagnosed hypertension. INTERVENTION: Community based hypertension screening among older adults in 2011-12. MAIN OUTCOME MEASURE: Blood pressure two years after initial screening. RESULTS: The intervention reduced systolic blood pressure: −6.3 mm Hg in the model without covariates (95% confidence interval −11.2 to −1.3) and −8.3 mm Hg (−13.6 to −3.1) in the model that adjusts additionally for demographic, social, and behavioural covariates. The impact on diastolic blood pressure was smaller and non-significant in all models. The results were similar when alternative functional forms were used to estimate the impact and the bandwidths around the intervention threshold were changed. The results did not vary by demographic and social subgroups. CONCLUSIONS: Community based hypertension screening and encouraging people with raised blood pressure to seek care and adopt blood pressure lowering behaviour changes could have important long term impact on systolic blood pressure at the population level. This approach could address the high burden of cardiovascular diseases in China and other countries with large unmet need for hypertension diagnosis and care.
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spelling pubmed-66194532019-07-28 Impact of community based screening for hypertension on blood pressure after two years: regression discontinuity analysis in a national cohort of older adults in China Chen, Simiao Sudharsanan, Nikkil Huang, Feng Liu, Yuanli Geldsetzer, Pascal Bärnighausen, Till BMJ Research OBJECTIVE: To estimate the causal impact of community based blood pressure screening on subsequent blood pressure levels among older adults in China. DESIGN: Regression discontinuity analysis using data from a national cohort study. SETTING: 2011-12 and 2014 waves of the Chinese Longitudinal Healthy Longevity Survey, a national cohort of older adults in China. PARTICIPANTS: 3899 older adults who had previously undiagnosed hypertension. INTERVENTION: Community based hypertension screening among older adults in 2011-12. MAIN OUTCOME MEASURE: Blood pressure two years after initial screening. RESULTS: The intervention reduced systolic blood pressure: −6.3 mm Hg in the model without covariates (95% confidence interval −11.2 to −1.3) and −8.3 mm Hg (−13.6 to −3.1) in the model that adjusts additionally for demographic, social, and behavioural covariates. The impact on diastolic blood pressure was smaller and non-significant in all models. The results were similar when alternative functional forms were used to estimate the impact and the bandwidths around the intervention threshold were changed. The results did not vary by demographic and social subgroups. CONCLUSIONS: Community based hypertension screening and encouraging people with raised blood pressure to seek care and adopt blood pressure lowering behaviour changes could have important long term impact on systolic blood pressure at the population level. This approach could address the high burden of cardiovascular diseases in China and other countries with large unmet need for hypertension diagnosis and care. BMJ Publishing Group Ltd. 2019-07-11 /pmc/articles/PMC6619453/ /pubmed/31296584 http://dx.doi.org/10.1136/bmj.l4064 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Research
Chen, Simiao
Sudharsanan, Nikkil
Huang, Feng
Liu, Yuanli
Geldsetzer, Pascal
Bärnighausen, Till
Impact of community based screening for hypertension on blood pressure after two years: regression discontinuity analysis in a national cohort of older adults in China
title Impact of community based screening for hypertension on blood pressure after two years: regression discontinuity analysis in a national cohort of older adults in China
title_full Impact of community based screening for hypertension on blood pressure after two years: regression discontinuity analysis in a national cohort of older adults in China
title_fullStr Impact of community based screening for hypertension on blood pressure after two years: regression discontinuity analysis in a national cohort of older adults in China
title_full_unstemmed Impact of community based screening for hypertension on blood pressure after two years: regression discontinuity analysis in a national cohort of older adults in China
title_short Impact of community based screening for hypertension on blood pressure after two years: regression discontinuity analysis in a national cohort of older adults in China
title_sort impact of community based screening for hypertension on blood pressure after two years: regression discontinuity analysis in a national cohort of older adults in china
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619453/
https://www.ncbi.nlm.nih.gov/pubmed/31296584
http://dx.doi.org/10.1136/bmj.l4064
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