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Cardiovascular effects of intravenous colforsin in normal and acute respiratory acidosis canine models: A dose-response study
In acidosis, catecholamines are attenuated, and higher doses are often required to improve cardiovascular function. Colforsin activates adenylate cyclase in cardiomyocytes without beta-adrenoceptor. Here, six beagles were administered colforsin or dobutamine four times during eucapnia (partial press...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619603/ https://www.ncbi.nlm.nih.gov/pubmed/31291253 http://dx.doi.org/10.1371/journal.pone.0213414 |