Single nucleotide polymorphisms associated with elevated alanine aminotransferase in patients receiving asunaprevir plus daclatasvir combination therapy for chronic hepatitis C

AIMS: Drug-induced liver damage characterized by serum alanine aminotransferase (ALT) elevation often occurs in direct-acting antiviral (DAA) combination therapy for chronic hepatitis C virus (HCV) infection. This study explored single nucleotide polymorphisms (SNPs) at drug metabolism- or transport...

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Detalles Bibliográficos
Autores principales: Kato, Keizo, Shimada, Noritomo, Atsukawa, Masanori, Abe, Hiroshi, Itokawa, Norio, Matsumoto, Yoshihiro, Agata, Rie, Tsubota, Akihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619746/
https://www.ncbi.nlm.nih.gov/pubmed/31291311
http://dx.doi.org/10.1371/journal.pone.0219022

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