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Mouse HSA(+) immature cardiomyocytes persist in the adult heart and expand after ischemic injury
The assessment of the regenerative capacity of the heart has been compromised by the lack of surface signatures to characterize cardiomyocytes (CMs). Here, combined multiparametric surface marker analysis with single-cell transcriptional profiling and in vivo transplantation identify the main mouse...
Autores principales: | Valente, Mariana, Resende, Tatiana Pinho, Nascimento, Diana Santos, Burlen-Defranoux, Odile, Soares-da-Silva, Francisca, Dupont, Benoit, Cumano, Ana, Pinto-do-Ó, Perpétua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619826/ https://www.ncbi.nlm.nih.gov/pubmed/31246945 http://dx.doi.org/10.1371/journal.pbio.3000335 |
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