Loss of ASAP1 in mice impairs adipogenic and osteogenic differentiation of mesenchymal progenitor cells through dysregulation of FAK/Src and AKT signaling

ASAP1 is a multi-domain adaptor protein that regulates cytoskeletal dynamics, receptor recycling and intracellular vesicle trafficking. Its expression is associated with poor prognosis for a variety of cancers, and promotes cell migration, invasion and metastasis. Little is known about its physiolog...

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Detalles Bibliográficos
Autores principales: Schreiber, Caroline, Saraswati, Supriya, Harkins, Shannon, Gruber, Annette, Cremers, Natascha, Thiele, Wilko, Rothley, Melanie, Plaumann, Diana, Korn, Claudia, Armant, Olivier, Augustin, Hellmut G., Sleeman, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619832/
https://www.ncbi.nlm.nih.gov/pubmed/31246957
http://dx.doi.org/10.1371/journal.pgen.1008216

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