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Conformational change within the extracellular domain of B cell receptor in B cell activation upon antigen binding

B lymphocytes use B cell receptors (BCRs) to recognize antigens. It is still not clear how BCR transduces antigen-specific physical signals upon binding across cell membrane for the conversion to chemical signals, triggering downstream signaling cascades. It is hypothesized that through a series of...

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Detalles Bibliográficos
Autores principales:	Shen, Zhixun, Liu, Sichen, Li, Xinxin, Wan, Zhengpeng, Mao, Youxiang, Chen, Chunlai, Liu, Wanli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620044/ https://www.ncbi.nlm.nih.gov/pubmed/31290744 http://dx.doi.org/10.7554/eLife.42271

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