GP38-targeting monoclonal antibodies protect adult mice against lethal Crimean-Congo hemorrhagic fever virus infection

Crimean-Congo hemorrhagic fever virus (CCHFV) is an important human pathogen. Limited evidence suggests that antibodies can protect humans against lethal CCHFV disease but the protective efficacy of antibodies has never been evaluated in adult animal models. Here, we used adult mice to investigate t...

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Detalles Bibliográficos
Autores principales: Golden, Joseph W., Shoemaker, Charles J., Lindquist, Michael E., Zeng, Xiankun, Daye, Sharon P., Williams, Janice A., Liu, Jun, Coffin, Kayla M., Olschner, Scott, Flusin, Olivier, Altamura, Louis A., Kuehl, Kathleen A., Fitzpatrick, Collin J., Schmaljohn, Connie S., Garrison, Aura R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620094/
https://www.ncbi.nlm.nih.gov/pubmed/31309159
http://dx.doi.org/10.1126/sciadv.aaw9535

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