Molecular basis of tRNA recognition by the Elongator complex

The highly conserved Elongator complex modifies transfer RNAs (tRNAs) in their wobble base position, thereby regulating protein synthesis and ensuring proteome stability. The precise mechanisms of tRNA recognition and its modification reaction remain elusive. Here, we show cryo–electron microscopy s...

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Detalles Bibliográficos
Autores principales: Dauden, Maria I., Jaciuk, Marcin, Weis, Felix, Lin, Ting-Yu, Kleindienst, Carolin, Abbassi, Nour El Hana, Khatter, Heena, Krutyhołowa, Rościsław, Breunig, Karin D., Kosinski, Jan, Müller, Christoph W., Glatt, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620098/
https://www.ncbi.nlm.nih.gov/pubmed/31309145
http://dx.doi.org/10.1126/sciadv.aaw2326

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