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Mdivi-1 and mitochondrial fission: recent insights from fungal pathogens

Mitochondrial fission shows potential as a therapeutic target in non-infectious human diseases. The compound mdivi-1 was identified as a mitochondrial fission inhibitor that acts against the evolutionarily conserved mitochondrial fission GTPase Dnm1/Drp1, and shows promising data in pre-clinical mod...

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Detalles Bibliográficos
Autores principales: Koch, Barbara, Traven, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620241/
https://www.ncbi.nlm.nih.gov/pubmed/30783741
http://dx.doi.org/10.1007/s00294-019-00942-6

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