Progress and Challenges for Live-cell Imaging of Genomic Loci Using CRISPR-based Platforms

Chromatin conformation, localization, and dynamics are crucial regulators of cellular behaviors. Although fluorescence in situ hybridization-based techniques have been widely utilized for investigating chromatin architectures in healthy and diseased states, the requirement for cell fixation preclude...

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Detalles Bibliográficos
Autores principales: Wu, Xiaotian, Mao, Shiqi, Ying, Yachen, Krueger, Christopher J., Chen, Antony K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620262/
https://www.ncbi.nlm.nih.gov/pubmed/30710789
http://dx.doi.org/10.1016/j.gpb.2018.10.001

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