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Structural characterization of life-extending Caenorhabditis elegans Lipid Binding Protein 8
The lysosome plays a crucial role in the regulation of longevity. Lysosomal degradation is tightly coupled with autophagy that is induced by many longevity paradigms and required for lifespan extension. The lysosome also serves as a hub for signal transduction and regulates longevity via affecting n...
Autores principales: | Tillman, Matthew C., Khadka, Manoj, Duffy, Jonathon, Wang, Meng C., Ortlund, Eric A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620326/ https://www.ncbi.nlm.nih.gov/pubmed/31292465 http://dx.doi.org/10.1038/s41598-019-46230-8 |
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