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Fatty acid desaturase 2 is up-regulated by the treatment with statin through geranylgeranyl pyrophosphate-dependent Rho kinase pathway in HepG2 cells

Statins have been reported to increase the plasma concentration of arachidonic acid (AA), an omega-6 long chain polyunsaturated fatty acid (LCPUFA) in several clinical studies indicating that statins affect the endogenous synthesis of LCUFAs. In the present study, we investigated the roles of the in...

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Detalles Bibliográficos
Autores principales:	Tanaka, Shou, Ishihara, Noriko, Suzuki, Sawako, Watanabe, Yasuhiro, Nagayama, Daiji, Yamaguchi, Takashi, Ohira, Masahiro, Saiki, Atsuhito, Tanaka, Tomoaki, Tatsuno, Ichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620338/ https://www.ncbi.nlm.nih.gov/pubmed/31292513 http://dx.doi.org/10.1038/s41598-019-46461-9

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