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Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis
Cerebellar neuronal progenitors undergo a series of divisions before irreversibly exiting the cell cycle and differentiating into neurons. Dysfunction of this process underlies many neurological diseases including ataxia and the most common pediatric brain tumor, medulloblastoma. To better define th...
Autores principales: | Penas, Clara, Maloof, Marie E., Stathias, Vasileios, Long, Jun, Tan, Sze Kiat, Mier, Jose, Fang, Yin, Valdes, Camilo, Rodriguez-Blanco, Jezabel, Chiang, Cheng-Ming, Robbins, David J., Liebl, Daniel J., Lee, Jae K., Hatten, Mary E., Clarke, Jennifer, Ayad, Nagi G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620341/ https://www.ncbi.nlm.nih.gov/pubmed/31292434 http://dx.doi.org/10.1038/s41467-019-10799-5 |
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