Combined Analysis of Methylation and Gene Expression Profiles in Separate Compartments of Small Bowel Mucosa Identified Celiac Disease Patients’ Signatures

By GWAS studies on celiac disease, gene expression was studied at the level of the whole intestinal mucosa, composed by two different compartments: epithelium and lamina propria. Our aim is to analyse the gene-expression and DNA methylation of candidate genes in each of these compartments. Epitheliu...

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Detalles Bibliográficos
Autores principales: Cielo, D., Galatola, M., Fernandez-Jimenez, N., De Leo, L., Garcia-Etxebarria, K., Loganes, C., Tommasini, A., Not, T., Auricchio, R., Greco, L., Bilbao, J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620355/
https://www.ncbi.nlm.nih.gov/pubmed/31292504
http://dx.doi.org/10.1038/s41598-019-46468-2

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